I just finished reading issue 75 of Fables.
Issue 75 is a culmination of all of the previous issues storylines. It truly is an epic series and possibly one of the best i have ever read.
The last batch of issues have been about the war of the fables against the adversary. It does not disappoint. I was worried for a while that the writer was going to resort to an after the fact narration for the whole telling of the war. This felt detaching and removed the reader from the intensity that would have been the war. Thankfully this plot device is not used much at all in issue 75 and it is full of fantastic twists and turns.
Do yourself a favor and start from issue number 1. You will be pleasantly surprised.